factor v leiden造句

• "' Factor V Leiden thrombophilia "'is a genetic disorder of blood clotting.
• The best known and most common hereditary form is Factor V Leiden.
• Like factor V Leiden, this abnormality is uncommon in Africans and Asians.
• Factor V Leiden increases the risk of venous thrombosis by two known mechanisms.
• The most common problem is the factor V Leiden and prothrombin G20210A mutation.
• In people with thrombosis, 10 % have factor V Leiden.
• Factor V Leiden is an inherited disorder of blood clotting.
• In Factor V Leiden, a G1691A nucleotide replacement results in an R506Q amino acid mutation.
• Other genetic mutations cause APC resistance, but none to the extent that Factor V Leiden does.
• Around 5 % of APC resistance are not associated with the above mutation and Factor V Leiden.
• Factor V Leiden is the most common hereditary hypercoagulability ( prone to clotting ) disorder amongst ethnic Europeans.
• A point mutation in the gene encoding Factor V can lead to a hypercoagulability disorder called Factor V Leiden.
• In both methods, the time it takes for blood to clot is decreased in the presence of the factor V Leiden mutation.
• Prothrombin G20210A is not usually accompanied by other factor mutations ( i . e ., the most common is factor V Leiden ).
• In 1994 factor V Leiden, resistant to inactivation by protein C, was described; this abnormality is the most common genetic cause for thrombosis.
• Individuals heterozygous for the Factor V Leiden mutation carry a risk of venous thrombosis 5 7 times higher than in the general population.
• Blood tests ultimately showed she carries three mutations including prothrombin and Factor V Leiden, plus an autoimmune disorder that she thinks contributed to the problem.
• Factor V Leiden is present in 5 % of the population of Northern European descent, but much rarer in those of Asian or African extraction.
• Among researchers using the term, it has been described as a coagulation disorder that can present in conjunction with protein S deficiency and Factor V Leiden.
• To rule out other causes for hypercoagulable state, it may be appropriate to check the antithrombin, protein C, protein S, factor V Leiden, and prothrombin G20210A.